Is Losartan Safe During Pregnancy?

Losartan in pregnancy: how to think about it

MotherToBaby says pregnant women are usually recommended to stop losartan under healthcare-provider guidance. The FDA Cozaar label warns that medicines acting on the renin-angiotensin system can injure or even cause death to the developing fetus when used in the second and third trimesters.

Checking a different medicine? The Pregnancy Medication Safety Hub collects all 154 SafeMama medicine guides, including the active-ingredient and dose questions worth raising with a pharmacist.

Losartan: safer choices

• Call the prescriber and pregnancy clinician promptly if you are pregnant or trying to conceive while taking losartan.
• Ask what pregnancy-compatible blood-pressure medicine and monitoring plan should replace it.
• Share dose, last tablet date, blood-pressure readings, kidney history, diabetes history, and any other blood-pressure medicines.

Losartan: what to avoid or double-check

• Avoid continuing losartan in pregnancy unless a specialist gives explicit direction.
• Avoid stopping without a replacement blood-pressure plan because uncontrolled hypertension can also be dangerous.
• Avoid assuming first-trimester exposure and second- or third-trimester exposure have the same risk profile.

How SafeMama helps

SafeMama can flag losartan, Cozaar, valsartan, olmesartan, telmisartan, ARB wording, ACE inhibitors and pregnancy-switch questions on medicine labels.

Open the SafeMama app, scan the barcode or search the ingredient, then use the result as a starting point for a conversation with your healthcare provider.

Sources

• MotherToBaby losartan fact sheet
• FDA Cozaar label
• ACOG chronic hypertension in pregnancy
• MotherToBaby ACE inhibitors fact sheet