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Disclaimer: This guide is for education only and is not a substitute for professional medical advice. Always confirm medicine, supplement and product decisions with your obstetrician, midwife, pharmacist or healthcare provider.

Medication

Is Losartan Safe During Pregnancy?

Published 2026-07-24 | By SafeMama Editorial Team | Editorial policy

Is Losartan Safe During Pregnancy? pregnancy safety guide image

Short answer

Losartan is usually stopped in pregnancy under clinician guidance because ARB medicines can cause serious fetal kidney and amniotic-fluid problems, especially later in pregnancy.

Usually switch under medical guidance

What is the safest way to think about this?

MotherToBaby says pregnant women are usually recommended to stop losartan under healthcare-provider guidance. The FDA Cozaar label warns that medicines acting on the renin-angiotensin system can injure or even cause death to the developing fetus when used in the second and third trimesters.

What is generally okay?

  • Call the prescriber and pregnancy clinician promptly if you are pregnant or trying to conceive while taking losartan.
  • Ask what pregnancy-compatible blood-pressure medicine and monitoring plan should replace it.
  • Share dose, last tablet date, blood-pressure readings, kidney history, diabetes history, and any other blood-pressure medicines.

What should you avoid or double-check?

  • Avoid continuing losartan in pregnancy unless a specialist gives explicit direction.
  • Avoid stopping without a replacement blood-pressure plan because uncontrolled hypertension can also be dangerous.
  • Avoid assuming first-trimester exposure and second- or third-trimester exposure have the same risk profile.

How SafeMama helps

SafeMama can flag losartan, Cozaar, valsartan, olmesartan, telmisartan, ARB wording, ACE inhibitors and pregnancy-switch questions on medicine labels.

Open the SafeMama app, scan the barcode or search the ingredient, then use the result as a starting point for a conversation with your healthcare provider.

Sources

Frequently asked questions

What if I took losartan before a positive pregnancy test?

Contact your clinician promptly with dose and dates. They can switch treatment, document timing, and decide whether any extra monitoring is needed.

Can I stop losartan today?

Call your clinician urgently for instructions. Many people need a safer replacement medicine so blood pressure does not rebound or stay uncontrolled.

Is losartan like lisinopril?

They are different classes, but both affect the renin-angiotensin system and require prompt pregnancy review.

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