Skip to main content
SafeMama

Disclaimer: This guide is for education only and is not a substitute for professional medical advice. Always confirm medicine, supplement and product decisions with your obstetrician, midwife, pharmacist or healthcare provider.

Medication

Is Reglan (Metoclopramide) Safe During Pregnancy?

Published 2026-07-14 | By SafeMama Editorial Team | Editorial policy

Is Reglan (Metoclopramide) Safe During Pregnancy? pregnancy safety guide image

Short answer

Reglan contains metoclopramide and may be prescribed for pregnancy nausea, vomiting, reflux-related symptoms, or delayed stomach emptying when a clinician decides the benefits outweigh side effects.

Sometimes prescribed; review side effects

What is the safest way to think about this?

MotherToBaby says metoclopramide exposure has not been shown to increase the chance of birth defects and has not been shown to increase some other pregnancy-related problems. The cautious part is side-effect monitoring and whether symptoms need a broader nausea plan.

What is generally okay?

  • Use metoclopramide only as prescribed and ask how long you should take it.
  • Tell your clinician about depression, anxiety, movement disorders, Parkinson disease, seizure history, or other nausea medicines.
  • Seek care if you cannot keep fluids down, have dehydration signs, weight loss, fainting, or reduced urination.

What should you avoid or double-check?

  • Avoid borrowing Reglan or combining it with other nausea medicines without medical advice.
  • Avoid ignoring restlessness, unusual movements, severe sleepiness, mood changes, or allergic symptoms.
  • Avoid delaying urgent care for severe vomiting or hyperemesis symptoms.

How SafeMama helps

SafeMama can identify metoclopramide, Reglan, anti-nausea medicines, and overlapping sedating ingredients so users can bring the exact medication list to their care team.

Open the SafeMama app, scan the barcode or search the ingredient, then use the result as a starting point for a conversation with your healthcare provider.

Sources

Frequently asked questions

Is Reglan first-line for morning sickness?

Many clinicians start with diet changes, vitamin B6, doxylamine, or other options first. Reglan may be considered when symptoms need prescription treatment.

What side effects should I ask about?

Ask about sleepiness, diarrhea, restlessness, mood changes, and movement-related side effects, especially if you have neurologic or mental-health history.

When is vomiting during pregnancy urgent?

Call urgently if you cannot keep fluids down, have dehydration signs, dizziness, weight loss, severe abdominal pain, fever, or reduced urination.

Check products faster with SafeMama

SafeMama scans food, skincare, medicine and supplement labels and explains pregnancy-safety flags using published guidance from authorities like ACOG, NHS, FDA, CDC and WHO.

Download SafeMama